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PROF. JOSPHAT CLEMENT MATASYOH

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PERSONAL DETAILS
Designation
PROFESSOR
Corporate Email
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Job Category
Teaching
Phone Number
+254722871521
Division / Faculty
Faculty of Science
Directorate / Dept
DEPT. OF CHEMISTRY
Section
Njoro
Office Extension No.
3328
Address
Egerton
ACADEMIC QUALIFICATIONS

1992 – 1996: Ph.D. in Organic Chemistry (University of Tuebingen – Germany)

1989 – 1991: M.Sc. in Applied Chemistry (University of Malawi – Malawi)

1985 – 1988: BSc. in Chemistry (University of Nairobi)

FIELDS OF SPECIALIZATION
  • Organic Chemistry
  • Natural Products Chemistry
PROFESSIONAL QUALIFICATIONS

Professor of Organic Chemistry

MANAGEMENT TRAINING

Apr. – June 2008: Successfully attended a University Management course at the University of Kassel, Germany funded by the DAAD and did a project entitled: Reorganisation of Research Management as an Institutional Reputation Building Process. The case of Egerton University

WORK EXPERIENCE
  • 26th March 2013 to date: Professor of Organic Chemistry
  • 3rd March 2008 – 25th March 2013: Associate Professor of Organic Chemistry
  • 24th June 1999 – 2nd March 2008: Senior Lecturer in Chemistry
  • 13th Nov. 1996 – 23rd June 1999: Lecturer in Chemistry

EGERTON UNIVERSITY APPOINTMENTS

  • May 2019: Chairman, Department of Chemistry, Egerton University
  • June 2016: Chair, Faculty of Science Risk Management Committee
  • June 2017: Member, Research sub-Committee of the Senate
  • 22nd September 2015: Member, Research Oversight Committee of Egerton University
  • August 2014: Member of Editorial Board of Egerton University Journal
  • 26th March 2013: Member of Egerton University Senate
  • June 2012: Member, Faculty of Science Research Committee
  • 2009 – to date: Vice Chairman, Egerton University Senior Common Room
  • 2009 – 2011: Faculty representative to Quality Assurance Board and Chair Faculty Quality Assurance committee
  • 2007 – 2008: Secretary, Rapid Results Initiative Committee on improvement of library services in Egerton University
  • 2002 – 2008: Seminar Coordinator of Chemistry Department, Egerton University
  • 2002 – 2006: Academic advisor to Postgraduate students of Chemistry Department
  • 2001 – 2005: Member of Egerton University – Tea Research Foundation of Kenya MOU Committee

OTHER APPOINTMENTS

  • August 2010 – to date: Treasurer, Humboldt Alumni Association Kenya Chapter
  • 2004 - 2011: Vice Chairman of Kenya DAAD Scholars Association – Egerton Chapter
  • 2004 – 2007: Member of the Executive Committee of Natural Products Research Network for East and Central Africa (NAPRECA), Kenya Chapter
  • 2003 – 2008: Treasurer, Kenya Chemical Society, Nakuru Chapter

INTERNATIONAL APPOINTMENTS

  1. Ambassador Scientist in Kenya for the Alexander von Humboldt Foundation of Germany
  2. Member of the Committee of experts on the Round Table of the Government of Federal Republic of Germany on “Internationalization of Education, Science and Research”.
  3. Member of the Editorial Board of the international chemistry journal “Molecules”.
  4. Member of African – German Network of Excellence in Science
KEY PROJECTS

POST-DOCTORAL RESEARCH AWARDS/FELLOWSHIPS

  • May – July 2001: University of Tuebingen (Germany) - DAAD
  • May – July 2003: University of Tuebingen (Germany) - DAAD
  • Oct – Dec. 2004: Newe Yaar Research Centre (Israel) - USAID
  • May – June 2006: University of Tuebingen (Germany) - DAAD
  • Apr. – June 2008: University of Kassel (Germany) - DAAD
  • May – July 2009: University of Tuebingen (Germany) - DAAD
  • Sept09 – Aug10: University of Goettingen (Germany) - Humboldt Foundation
  • May – Oct 2011: Technical University of Berlin (Germany) - Humboldt Foundation
  • May – June 2014: Technical University of Berlin (Germany) - DAAD
  • June – August 2016: Technical University of Berlin (Germany) - Humboldt Foundation
  • July – December 2019: Technical University of Dortmund (Germany) - Humboldt Foundation

INTERNATIONAL RESEARCH VISITS

  • 20th – 26th August 2017: Catholic University of Leuven, Belgium. - VLIR-UOS Global minds programme
  • 1st – 30th July 2015 Helmholtz Centre for Research in Infectious Diseases in Braunschweig, Germany - ERAFRICA – ASAFEM Project
  • 10th – 25th April 2015 Helmholtz Centre for Research in Infectious Diseases in Braunschweig, Germany - Humboldt Foundation – Group Research Linkage
  • 20th – 26th June 2012: Technical University of Berlin (Germany) - German Ministry of Education and Research
  • Dec. 1994: Oklahoma Medical Research Foundation (USA) - OMRF/DAAD

EQUIPMENT GRANTS

  • 2001: Rotary evaporator - DAAD, 20,508.75 €
  • 2012: High Performance Liquid Chromatography (HPLC) - Humboldt Foundation, 15,900.00 €

EXTERNAL RESEARCH GRANTS

  • 2003: Biological Insect Control, USAID  – USA , Collaborator, US$ 199,000
  • 2008: Control of Moulds and Associated Mycotoxins in Foods - VicRes - SIDA , Principal investigator, US$ 150,000
  • 2012: Anthelmintic Secondary Metabolites from Indigenous African Plants and their Endophytes - BMBF (Mobility funds), Principal investigator, 15,000 €
  • 2013: Isolation of Bioactive Secondary Metabolites for the Control of Plant Pathogens in Maize and Beans. - The Humboldt Foundation, Principal investigator, 54,730 €
  • 2014: Antibiotics and anti-quorum sensing compounds from African fungal endophytes inhabiting medicinal plants and cultures of macromycetes - ERAFRICA – EU – Africa joint Funding; Principal investigator, 130,000 €
  • 2018: Development of biopesticides from medicinal plants and their microbial endophytes for the control of maize and bean pathogens = - National Research Fund - Kenya; Principal investigator, 100,000 €
  • 2018: Cosmetic products developed from two bioactive plant compounds, teaching, research and product development - BMBF/DAAD; Collaborating investigator, 1.1 Million €
  • 2020: Nematicidal and Antibiofilm metabolites from Kenyan Basidiomycota - The Humboldt Foundation; Principal investigator, 55.000 €
  • 2021: Mycobiomics - European Commission; Collaborator, 1,375,400.00

INTERNATIONAL RESEARCH COLLABORATIONS AND LINKAGES

  1. University of Tuebingen - Germany, Prof. Martin Maier
  2. Newe Yaar Research Centre - Israel, Prof. Uzi Ravid
  3. University of Goettingen - Germany, Prof. Hartmut Laatsch
  4. Technical University of Berlin - Germany, Prof. Roderich Suessmuth
  5. Helmholtz Centre for Research in Infectious Diseases in Braunschweig - Germany, Prof. Marc Stadler
  6. Catholic University of Leuven - Belgium, Prof. Walter Luyten
  7. Catholic University of Lovain - Belgium, Dr. Cony Decock
  8. University of Muenster - Germany, Prof. Thomas Schmidt
  9. University of Maryland - USA, Prof. Priscilla Chaverri
  10. University of KwaZulu Natal - South Africa, Dr. Hafiza Cheniah
  11. University of Pretoria - South Africa, Prof. Bernard Slippers
  12. Makerere University - Uganda, Dr. Jesca Nakavuma
  13. Technical University of Dortmund - Germany, Prof. Michael Spiteller
  14. University of Bremen - Germany, Prof. Peter Spiteller
RESEARCH INTERESTS

Isolation of antimicrobial, mosquito larvicidal, insecticidal, acaricidal and anthelmintic secondary metabolites from tropical fungi, medicinal plants and their endophytic microbes.

LIST OF PUBLICATIONS
  1. Comparison of the Secondary Metabolism of the Basidiomycetes Armillaria mellea and Desarmillaria ectypa. Jacklyne Chepkemoi, Sebastian Pfütze, Njogu M. Kimani, Josphat C Matasyoh, and Marc Stadler. Chem. Biodiversity 1-5 (2024).  https://doi.org/10.1002/cbdv.202400933      
  2. Secondary metabolites from the stem bark of Alstonia boonei and the seeds of Picralima nitida with antibacterial activities. Awodayo Oluwatoyin Adepitia, Divinah Kwamboka Nyambokia, Gebreheiwot Bedane Kibrom, Anthony Adebolu Elujoba, Michael Spiteller and Josphat Clement Matasyoh.Natural Product Research, 1-6 (2024). https://doi.org/10.1080/14786419.2024.2349254 
  3. In vitro and in silico studies reveal antidiabetic properties of arylbenzofurans from the root bark of Morus mesozygia Stapf. Katherine Olabanjo Olufolabo, Samuel Ayoolu Oguntimehin, Kai Lüersen, Vaderament-A. Nchiozem-Ngnitedem, Emmanuel Ayodeji Agbebi, Divinah Kwamboka Nyamboki, Kolade Olatubosun Faloye, Josphat Clement Matasyoh, Gerald Rimbach, Bernd Schmidt, Jones Olanrewaju Moody. Front. Pharmacol. 15:1338333 (2024). https://doi.10.3389/fphar.2024.1338333 
  4. Discovery of novel secondary metabolites from the basidiomycete Lentinus cf. sajor-caju and their inhibitory effects on Staphylococcus aureus biofilms. Haoxuan Zeng, Hedda Schrey, Marc Stadler, Cony Decock, Josphat Clement Matasyoh, Mathias Müsken. Fitoterapia 175  105904 (2024). https://doi.org/10.1016/j.fitote.2024.105904
  5. Recent progress in the evaluation of secondary metabolites from Basidiomycota. Winnie Chemutai Sum, Sherif S. Ebada, Josphat Clement Matasyoh, Marc Stadler. Current Research in Biotechnology 6  100155 (2023). https://doi.org/10.1016/j.crbiot.2023.100155
  6. Neurite Outgrowth-Inducing Drimane-Type Sesquiterpenoids Isolated from Cultures of the Polypore Abundisporus violaceus MUCL 56355. Winnie Chemutai Sum, Sherif S. Ebada, Marco Kirchenwitz, Lucy Wanga, Cony Decock, Theresia E. B. Stradal, Josphat Clement Matasyoh, Attila Mándi, Tibor Kurtán, and Marc Stadler.  https://doi.org/10.1021/acs.jnatprod.3c00525 
  7. Antidermatophytic quinolizidine alkaloids from Calpurnia aurea subsp.aurea (Aiton) Benth. Lucy Aketch Wanga, Abwao Stephen Indieka, Josphat Clement Matasyoh. Fitoterapia 171  105698 (2023). https://doi.org/10.1016/j.fitote.2023.105698
  8. Biologically active drimane derivatives isolated from submerged cultures of the wood-inhabiting basidiomycete Dentipellis fragilis. Nico Mitschke, Winnie Chemutai Sum, Khadija Hassan, Marco Kirchenwitz, Hedda Schrey, Luca Gerhards, Harald Kellner, Theresia E. B. Stradal, Josphat C. Matasyoh and Marc Stadler. RSC Adv. 13, 25752 (2023). https://DOI:10.1039/d3ra04204a  
  9. Two new lanostanoid glycosides isolated from a Kenyan polypore Fomitopsis carnea. Winnie Chemutai Sum, Sherif S. Ebada, Didsanutda Gonkhom, Cony Decock, Rémy Bertrand Teponno, Josphat Clement Matasyoh and Marc Stadler. Beilstein J. Org. Chem., 19, 1161–116 (2023). https://doi.org/10.3762/bjoc.19.84
  10. Hericioic Acids A−G and Hericiofuranoic Acid; Neurotrophic Agents from Cultures of the European Mushroom Hericium flagellum. Winnie Chemutai Sum, Sherif S. Ebada, Marco Kirchenwitz, Harald Kellner, Mahmoud A. A. Ibrahim, Theresia E. B. Stradal, Josphat Clement Matasyoh, and Marc Stadler. J. Agric. Food Chem. 71, 11094−11103 (2023). https://doi.org/10.1021/acs.jafc.3c02897 
  11. Bioactive compounds from Juniperus procera (Cupressaceae) with activity against common bean bacterial pathogens. Teresia Wangui Nduati, Isabel Nyokabi Wagara, Waudo Walyambillah, Beatrice Were and Josphat Clement Matasyoh. Afr. J. Biotechnol. 22(6),106-113 (2023). https://DOI:10.5897/AJB2023.17552  
  12. Bioactive compounds from Hagenia abyssinica with activity against bean pathogenic bacteria. Isabel Nyokabi Wagara, Waudo Walyambillah, Beatrice Were, David Muthama, Hellen Gathiru and Josphat Clement Matasyoh. Afr. J. Biotechnol. 22(5), 80-84 (2023). https://DOI:10.5897/AJB2022.17468  
  13. Heimionones A–E, New Sesquiterpenoids Produced by Heimiomyces sp., a Basidiomycete Collected in Africa. Sebastian Pfütze, Atchara Khamsim, Frank Surup, Cony Decock, Josphat C. Matasyoh, and Marc Stadler. Molecules, 28, 3723. (2023).  https://doi.org/10.3390/molecules28093723

  14. Calamene-Type Sesqui‑, Mero‑, and Bis-sesquiterpenoids from Cultures of Heimiomyces sp., a Basidiomycete Collected in Africa. Sebastian Pfütze, Atchara Khamsim, Frank Surup, Cony Decock, Josphat C. Matasyoh, and Marc Stadler. J. Nat. Prod. 86, 390−397 (2023)  https://doi.org/10.1021/acs.jnatprod.2c01015.

  15. Neurotrophic and Immunomodulatory Lanostane Triterpenoids from Wood-Inhabiting Basidiomycota. Khadija Hassan, Blondelle Matio Kemkuignou, Marco Kirchenwitz, Kathrin Wittstein, Monique Rascher-Albaghdadi, Clara Chepkirui, Josphat C. Matasyoh, Cony Decock, Reinhard W. Köster, Theresia E. B. Stradal and Marc Stadler. Int. J. Mol. Sci. 23, 13593, (2022). https://doi.org/10.3390/ijms232113593.
  16. Drimane-Type Sesquiterpenoids Derived from the Tropical Basidiomycetes Perenniporia centrali-africana and Cerrena sp. Nov. Paomephan Pathompong, Sebastian Pfütze, Frank Surup, Thitiya Boonpratuang, Rattaket Choeyklin, Josphat C. Matasyoh, Cony Decock, Marc Stadler, Chuenchit Boonchird. Molecules 27, 5968 (2022).
  17. Antimicrobial and Cytotoxic Cyathane-Xylosides from Cultures of the Basidiomycete Dentipellis fragilis. Winnie Chemutai Sum, Nico Mitschke, Hedda Schrey, Kathrin Wittstein, Harald Kellner, Marc Stadler, and Josphat Clement Matasyoh. Antibiotics, 11, 1072 (2022). https://doi.org/10.3390/antibiotics11081072
  18. Phytochemical Constituents of F. Sagittifolia Warburg ex Mildbraed & Burret Leaves with Antimicrobial Activity. Olayombo Margaret Taiwo, Olaoluwa Omosalewa Olaoluwa, Olapeju Oluyemisi Aiyelaagbe, Josphat Clement Matasyoh. Biology, Medicine, & Natural Product Chemistry, 11(1), 75-81 (2022). https://DOI:10.14421/biomedich.2022.111.75-81
  19. Meroterpenoids Possibly Produced by a Bacterial Endosymbiont of the Tropical Basidiomycete Echinochaete brachypora. Khadija Hassan, Clara Chepkirui, Natalia Andrea Llanos-López, Josphat C. Matasyoh, Cony Decock, Yasmina Marin-Felix, and Marc Stadler. Biomolecules 12, 755 (2022). https://doi.org/10.3390/biom12060755
  20. Phytochemical composition and in vitro antileishmanial activity of Bidens pilosa, Tithonia diversifolia and Sonchus oleraceus extracts. Thomas O. Momanyi, Josphat C. Matasyoh, Stephen M. Karori and Johnstone M. Ingonga. Journal of Medicinal Plants Research. 16(6), 205-213 (2022). https://DOI:10.5897/JMPR2019.6839
  21. Chemical characterization of Kenyan Cupressus lusitanica Mill., Ocimum americanum L. and Lippia Javanica (Burm.f.) Spreng essential oils. Philip Kandgor Bett, Joshua Ondura Ogendo, Josphat Clement Matasyoh and Ann Jepkorir Kiplagat. Afr. J. Environ. Sci. Technol. 16(2), 79-90 (2022). https://DOI:10.5897/AJEST2021.3083

  22. Cytotoxic compounds from the leaf of Bersama abyssinica subspecies abyssinica. Divinah Kwamboka Nyamboki, Kibrom Gebreheiwot Bedane, Khadija Hassan, Michael Spiteller, Josphat Clement Matasyoh. Phytochemistry 198, 113153 (2022).   https://doi.org/10.1016/j.phytochem.2022.113153

  23. Cytotoxic Compounds from the Stem Bark of Two subsp. of Bersama abyssinica. Divinah K. Nyamboki, Kibrom G. Bedane, Khadija Hassan, Lukas Brieger, Carsten Strohmann, Michael Spiteller, and Josphat C. Matasyoh. J. Nat. Prod. 84, 1453−1458 (2021) https://doi.org/10.1021/acs.jnatprod.0c01141

  24. Investigating the Antifungal Mechanism of Action of Polygodial by Phenotypic Screening in Saccharomyces cerevisiae. Purity N. Kipanga, Liesbeth Demuyser, Johannes Vrijdag, Elja Eskes, Petra D’hooge, Josphat Matasyoh, Geert Callewaert, Joris Winderickx, Patrick Van Dijck and Walter Luyten. Int. J. Mol. Sci. 22, 5756 (2021). https://doi.org/10.3390/ijms22115756  

  25. Anti-bacterial activity of secondary metabolites from Chrysanthemum cinerariaefolium. Caroline J. Kosgei, Festus Tolo, Josphat C. Matasyoh, Meshack Obonyo, Peter Mwitari, Lucia Keter, Richard Korir and Beatrice Irungu. J. Med. Plants Res. 15(6), 241-251 (2021)
  26. Synthesis of Silver Nanoparticles Using Dichloromethane - Methanol Flower Extract of Chrysanthemum cinerariaefolium and Its Antibacterial Activity. Caroline Jepchirchir Kosgei, Festus Tolo, Josphat Clement Matasyoh, Meshack Obonyo, Peter Mwitari, Lucia Keter, James Jorum Owuor, Moses Ollengo, Beatrice Irungu. American Journal of Nano Research and Applications. 9(1), 1-8 (2021).
  27. Antibacterial activity of endophytic fungi isolated from leaves of medicinal Plant Leucas martinicensis L. growing in a Kenyan tropical forest. Ruth Moraa Obare, Stephen A. Indieka and Josphat Matasyoh. Afr. J. Biochem. Res. 14(3), 81-91 (2020). https://academicjournals.org/journal/AJBR/article-full-text-pdf/FA93F1264712
  28. Hypoglycaemic effect   of Salvia officinalis extracts on alloxan-induced diabetic Swiss albino mice. Kanana Faith  Mbiti, Maina Charles Mwendia, Kibet Joseph  Mutai, Josphat C. Matasyoh. Journal of Medicinal Plants Research. 14(10), 518-525 (2020). https://academicjournals.org/journal/JMPR/article-full-text-pdf/D45650A64727
  29. Heimiomycins A−C and Calamenens from the African Basidiomycete Heimiomyces sp. Tian Cheng, Clara Chepkirui, Cony Decock, Josphat C. Matasyoh, and Marc Stadler. J. Nat. Prod. 83, 8, 2501–2507 (2020). https://pubs.acs.org/doi/10.1021/acs.jnatprod.0c00486
  30. Biofilm inhibiting properties of compounds from the leaves of Warburgia ugandensis Sprague subsp ugandensis against Candida and staphylococcal biofilms. Purity N. Kipanga, Maoxuan Liu, Sujogya K. Panda, Anh Hung Mai, Cedrick Veryser, Luc Van Puyvelde, Wim M. De Borggraeve, Patrick Van Dijck, Josphat Matasyoh, Walter Luyten. Journal of Ethnopharmacology 248, 112352 (2020). https://doi.org/10.1016/j.jep.2019.112352
  31. Two New Aliphatic Alkenol Geometric Isomers and a Phenolic Derivate from Endophytic Fungus Diaporthe sp. Host to Syzygium cordatum (Myrtaceae). Towett Kipngetich Erick, Joyce Kiplimo, Josphat Matasyoh. Science letters, 7(3):108-118 (2019).
  32. Skeletocutins M-Q, biologically active compounds from the fruiting bodies of the basidiomycete Skeletocutis sp. collected in Africa. Tian Cheng, Clara Chepkirui, Cony Decock, Josphat C. Matasyoh and Marc Stadler. Beilstein J. Org. Chem. 15, 2782–2789 (2019). https://doi.org/10.3762/bjoc.15.270
  33. Skeletocutins A-L: Antibacterial Agents from the Kenyan Wood-inhabiting Basidiomycete, Skeletocutis sp. Chepkirui C, Cheng T, Sum BW, Decock C, Matasyoh JC, Praditya DF, Steinmann E, Stadler M. J. Agric. Food Chem. 67, 8468−8475 (2019). http://dx.doi.org/10.1021/acs.jafc.9b02598
  34. Sesquiterpenes from an Eastern African medicinal mushroom belonging to the genus Sanghuangporus. Cheng T, Chepkirui C, Decock C, Matasyoh JC, and Stadler M. J. Nat. Prod. 82(5), 1283-1291 (2019). http://DOI:10.1021/acs.jnatprod.8b01086
  35. Preparation of Sesquiterpene Lactone-Loaded PLA Nanoparticles and Evaluation of Their Antitrypanosomal Activity. Njogu M. Kimani, Solveig Backhaus, Josphat C. Matasyoh, Marcel Kaiser, Fabian C. Herrmann, Thomas J. Schmidt, and Klaus Langer. Molecules 24, 2110 (2019). http://doi:10.3390/molecules24112110  
  36. Antibacterial saponins from the leaves of Polyscias fulva (Araliaceae). Winnie Cherotich Maritim, Isabel Nyokabi Wagara and Josphat Clement Matasyoh. Afr. J. Biotechnol. 18(19), 390-398, (2019). http://DOI:10.5897/AJB2018.16484
  37. Antimicrobial activity of Basidiomycetes fungi isolated from a Kenyan tropical forest. Winnie Chemutai Sum, Stephen Abwao Indieka and Josphat Clement Matasyoh. Afr. J. Biotechnol. 18(5), 112-123, (2019). https://doi.org/10.5897/AJB2018.16660
  38. Complementary Quantitative Structure–Activity Relationship Models for the Antitrypanosomal Activity of Sesquiterpene Lactones. Njogu M. Kimani, Josphat C. Matasyoh, Marcel Kaiser, Mauro S. Nogueira, Gustavo H. G. Trossini and Thomas J. Schmidt. Int. J. Mol. Sci. 19, 3721, (2018).
  39. An unprecedented spiro [furan-2,1’-indene]-3-one derivative and other nematicidal and antimicrobial metabolites from Sanghuangporus sp. (Hymenochaetaceae, Basidiomycota) collected in Kenya. Clara Chepkirui, Tian Cheng, Josphat Matasyoh, Cony Decock, Marc Stadler. Phytochemistry Letters 25, 141–146, (2018). https://doi.org/10.1016/j.phytol.2018.04.022
  40. Microporenic Acids A–G, Biofilm Inhibitors, and Antimicrobial Agents from the Basidiomycete Microporus Species. Clara Chepkirui, Kamila T. Yuyama, Lucy A. Wanga, Cony Decock, Josphat C. Matasyoh, Wolf-Rainer Abraham, and Marc Stadler. J. Nat. Prod., 81(4), 778–784, (2018). http://dx.doi.org/10.1021/acs.jnatprod.7b00764
  41. Aethiopinolones A–E, New Pregnenolone Type Steroids from the East African Basidiomycete Fomitiporia aethiopica. Clara Chepkirui, Winnie C. Sum, Tian Cheng, Josphat C. Matasyoh, Cony Decock and Marc Stadler. Molecules, 23, 369 (2018). http://DOI:10.3390/molecules23020369
  42. Antimicrobial activity of metabolites extracted from Zanthoxylum gilletii, Markhamia lutea and their endophytic fungi against common bean bacterial pathogens. Lucy Aketch Wanga, Isabel Nyokabi Wagara, Ramadhan Mwakubambanya and Josphat Clement Matasyoh.    Afr. J. Biotechnol. 17(26), 870-879, (2018). http://DOI:10.5897/AJB2018.16463    
  43. Two withanolides from Withania somnifera (Solanaceae) and activity of methanolic extracts against fungal and bacterial pathogens that affects food crops. Regina Chepkorir, Josphat Clement Matasyoh and Isabel N. Wagara. Afr. J. Food Sci. 12(5) 115-125, (2018). http://DOI:10.5897/AJFS2016.1503
  44. Sesquiterpene Lactones from Vernonia cinerascens Sch. Bip. and Their in vitro Antitrypanosomal Activity. Njogu M. Kimani, Josphat C. Matasyoh, Marcel Kaiser, Reto Brun and Thomas J. Schmidt. Molecules, 23(2), 248, (2018). http://dx.doi.org/10.3390/molecules23020248
  45. Antiprotozoal Sesquiterpene Lactones and Other Constituents from Tarchonanthus camphoratus and Schkuhria pinnata. Njogu M. Kimani, Josphat C. Matasyoh, Marcel Kaiser, Reto Brun, and Thomas J. Schmidt. J. Nat. Prod., 81(1), 124–130 (2018). http://dx.doi.org/10.1021/acs.jnatprod.7b00747
  46. Two cytotoxic triterpenes from cultures of a Kenyan Laetiporus sp. (Basidiomycota). Clara Chepkirui, Josphat Clement Matasyoh, Cony Decock, Marc Stadler. Phytochemistry Letters 20, 106 – 110 (2017). http://dx.doi.org/10.1016/j.phytol.2017.04.009  
  47. Anti-Trypanosomatid Elemanolide Sesquiterpene Lactones from Vernonia lasiopus O. Hoffm Njogu M. Kimani, Josphat C. Matasyoh, Marcel Kaiser, Reto Brun, Thomas J. Schmidt. Molecules. 22, 597, (2017). http://doi:10.3390/molecules22040597    
  48. Monochlorinated calocerins A-D and 9-oxostrobilurin derivatives from the basidiomycete Favolaschia calocera. Clara Chepkirui, Christian Richter, Josphat Clement Matasyoh, Marc Stadler. Phytochemistry 132, 95-101, (2016). http://dx.doi.org/10.1016/j.phytochem.2016.10.001
  49. Laxitextines A and B, Cyathane Xylosides from the Tropical Fungus Laxitextum incrustatum. Cynthia M. Mudalungu, Christian Richter,  Kathrin Wittstein, Muna Ali Abdalla, Josphat C. Matasyoh, Marc Stadler, and Roderich D. Suessmuth. J. Nat. Prod. 2016, 79, 894−898. http://dx.doi.org/10.1021/acs.jnatprod.5b00950
  50. Isolation, Structure Elucidation and Larvicidal Activity of Laggera alata Extracts. Ollengo Moses A., Vulule John M., Matasyoh Josphat C. Research Journal of Pharmacognosy and Phytochemistry. 8(3), 153 – 164 (2016). http://DOI:10.5958/0975-4385.2016.00027.3
  51. Chemical composition and antifungal activity of the essential oil from Lippia javanica (Verbenaceae) Yegon K. Philemon, Josphat C. Matasyoh, and Isabel N. Wagara. International Journal of Biotechnology and Food Science. 4(1), 1-6, (2015). http://DOI:10.5897/AJB2018.16463
  52. In vitro Assessment of Pentacyclic Triterpenoids from Leaves of Pittosporum viridiflorum against East Coast Fever Vector Rhipicephalus appendiculatus. Christine T. Nyabayo, Josphat C. Matasyoh, Charles Mwendia.  American Journal of Chemistry and Application. 2(6), 95-100, (2015).
  53. Acaricidal Coumarins from the Medicinal Plant Acokanthera schimperi. Jared O. Owino, Josphat C. Matasyoh, Abdi A. Guliye. Organic and Inorganic Chemistry 1(3), 1-6 (2015).
  54. Two polymethoxylated flavonoids with antioxidant activities and a rearranged clerodane diterpenoid from the leaf exudates of Microglossa pyrifolia. Aggrey  Akimanya,  Jacob  O.  Midiwo, Josphat  Matasyoh,  Francis  Okanga, Veronica M.  Masila, Larry Walker,  Babu  L. Tekwani, Ilias Muhammad, Leonidah Kerubo Omosa. Phytochemistry Letters 11, 183–187, (2015). http://dx.doi.org/10.1016/j.phytol.2014.12.008
  55. Chemical composition and acaricidal activity of Salvia nilotica essential oil against Rhipicephalus Appendiculatus. Christine T. Nyabayo, Josphat C. Matasyoh, Charles Mwendia. Advancement in Medicinal Plant Research. 3(2), 46-54, (2015).
  56. Antimicrobial assay and phytochemical analysis of Solanum nigrum complex growing in Kenya. Lexa G. Matasyoh, Hellen M. Murigi, Josphat C. Matasyoh. African Journal of Microbiology Research, 3923 – 3930, (2014). https://doi.org/10.5897/AJMR2014.7133
  57. Chemical composition and larvicidal activity of Zanthoxylum gilletii essential oil against Anopheles gambiae. Ombito O. Japheth, Matasyoh C. Josphat, Vulule M. John. African Journal of Biotechnology. 13(21), 2175 – 2180, (2014). http://dx.doi.org/10.1016/j.bmc.2011.10.076
  58. Chemical composition and antihelmintic activity of Teclea nobilis essential oil against Schistosoma mansoni miracidia. Mark K. Njogu, Josphat C. Matasyoh, Alfred C. Kibor. J Pharm Biomed Sci. 4(10), 880 – 886, (2014).
  59. Chemical composition and larvicidal activity of essential oil of Lippia kituiensis against larvae of Rhipicephalus appendiculatus. Caroline J.  Kosgei, Josphat C. Matasyoh, Charles M. Mwendia, Samuel T. Kariuki, Abdi Y. Guliye. Int. J. Biol. Chem. Sci. 8(4), 1938-1947, (2014).
  60. Phytochemical Screening, Cytotoxity Studies and Larvicidal Activity of Hexane Extract of Lippia Kituensis Against Rhipicephalus Appendiculatus.  Caroline J.  Kosgei, Charles M. Mwendia, Charles G. Mwaniki, Josphat C. Matasyoh. J. Biomed. and Pharm. Res. 3(4), 105 – 110, (2014).
  61. Antifungal activity of Flavonoids isolated from Monanthotaxis littoralis against mycotoxigenic fungi from maize. Chepkirui Clara, Josphat C. Matasyoh, Isabel N. Wagara, Jesca Nakavuma. American Journal of Chemistry and Application. 1(4), 54-60, (2014)
  62. Endophytes as producers of peptides: An overview about the recently discovered Peptides from endophytic microbes. Muna Ali Abdalla, Josphat C. Matasyoh. Nat. Prod. Bioprospect.  4, 257–270 (2014). http://DOI:10.1007/s13659-014-0038-y  
  63. Isolation of Four Furoquinoline Alkaloids from Teclea Nobilis and their Activity against Schistosoma Mansoni Miracidia. Mark K. Njogu, Josphat C. Matasyoh, Alfred C. Kibor. Journal of Biomedical and Pharmaceutical Research. 3(4), 87-93 (2014).
  64. Isolation of Mycotoxigenic Moulds Contaminating Maize and Groundnuts in Selected Districts in Kenya. Isabel N. Wagara, Josphat C. Matasyoh, Jesca L. Nakavuma. Res. J. Microbiol. 9(4), 177 – 188 (2014).
  65. Chemical composition and antifungal activity of Piper capense oil against mycotoxigenic Aspergillus, Fusarium and Penicillium species. Josphat C. Matasyoh, Isabel N. Wagara, Jesca L. Nakavuma, Regina Chepkorir. Int. J. Biol. Chem. Sci. 7(4): 1441 – 1451 (2013).
  66. Antifungal activity of Monathotaxis littoralis essential oil against mycotoxigenic fungi isolated from maize. Clara Chepkirui, Josphat C. Matasyoh, Isabel N. Wagara. Int. J. Microbiol. Res. Rev. 2(6), 103 – 109 (2013).
  67. Larvicidal compounds from Fagaropsis angolensis leaves against malaria vector (Anopheles gambiae). Mudalungu C. M., Matasyoh J. C., Vulule J. M., Chepkorir R. Int. J. Malaria Res. Rev. 1(1), 1-7 (2013).
  68. Inhibitory action of some essential oils on growth of various moulds isolated from dried maize grains. Janet N. Nyukuri, Isabel N. Wagara, Josphat C. Matasyoh, Jesca L. Nakavuma. Egerton J. Sci. & Technol. 13, 1 – 10 (2013).
  69. Management of stem borers using selected botanical pesticides in a maize bean cropping system. J. O. Ogendo, A. L. Deng, E. O. Omolo, J. C. Matasyoh, Tuey, R. K., Khan, Z. R. Egerton J. Sci. & Technol. 13, 21 – 38 (2013).
  70. Screening of Indigofera lupatana Baker F. root extracts for antibacterial activities. Sospeter N. Njeru, Charles M. Gathinji, Charles M. Maina, Josphat C. Matasyoh. Afr. J. Pharmacol. Ther. 1(3), 71 – 77 (2012).
  71. Antibacterial activity of methanol root extracts of Indigofera lupatana Baker F. Sospeter Njerua Ngocia, Josphat C. Matasyoh, Charles Gathinji Mwaniki Charles Maina Mwendia. Eastern Journal of Medicine 17, 11-16 (2012)
  72. Persipeptides A and B, Two Cyclic Peptides from Streptomyces sp. UTMC 1154. Fatemeh Mohammadipanah, Josphat Matasyoh, Javad Hamedi, Hans-Peter Klenk, Hartmut Laatsch.  Biorganic and Medicinal Chemistry 20, 335-339 (2011). http://dx.doi.org/10.1016/j.bmc.2011.10.076
  73. Larvicidal Activity of Acridone Alkaloids from Zanthoxylum leprieurii against the Malaria Vector Anopheles gambiae. Josphat C. Matasyoh, Ferdinand M. Talontsi, Rostand M. Ngoumfo, Regina Chepkorir. The Natural Products Journal. 1(2), 121 – 124 (2011).
  74. Chemical composition and larvicidal activity of Piper capense essential oil against the malaria vector, Anopheles gambiae. Josphat C. Matasyoh, Euty M. Wathuta, Samuel T. Kariuki, Regina Chepkorir. Journal of Asia-Pacific Entomology 14, 26–28 (2011). http://doi:10.1016/j.aspen.2010.11.005  
  75. Chemical composition of Cymbopogon citratus essential oil and its effect on mycotoxigenic Aspergillus species. Josphat C. Matasyoh, Isabel N. Wagara, Jesca L. Nakavuma, Anderson M. Kiburai. Afr. J. Food Sci. 5(3), 138-142 (2011).
  76. Mosquito larvicidal activity of alkaloids from Zanthoxylum lemairei against the malaria vector Anopheles gambiae. Ferdinand M. Talontsi, Josphat C. Matasyoh, Rostand M. Ngoumfo, Regina Chepkorir, Pesticide Biochemistry and Physiology 99, 82–85 (2011). http://dx.doi.org/10.1016/j.pestbp.2010.11.003
  77. Larvicidal Activity of Metabolites from the Endophytic Podospora sp. against the Malaria Vector Anopheles gambiae. Josphat C. Matasyoh, Birger Dittrich, Anja Schueffler, Hartmut Laatsch. Parasitol Res. 108, 561-566 (2011).
  78. Biocontrol Potential of selected Plant Essential Oil Constituents as Fumigants of Insect Pests Attacking Stored Food Commodities. J.O. Ogendo, A.L. Deng, M. Kostyukovsky, U. Ravid, J.C. Matasyoh, E.O. Omolo, S.T. Kariuki, A.W. Kamau, P.K. Bett, E. Shaaya. Baraton Interdisciplinary Research Journal 1(1), 13-19 (2011).
  79. Phytochemical Constituents and Antimicrobial Activity of Leaf Extracts of three Amaranthus Species. Z. C. Maiyo, R. M. Ngure, J. C. Matasyoh, R. Chepkorir. African Journal of Biotechnology 9 (21), 3178-3182 (2010). https://doi.org/10.5897/AJB2010.000-3162
  80. Chemical Composition and Antimicrobial Activity of Essential oil of Corriundrum sativum. J. C. Matasyoh, Z. C. Maiyo, R. M. Ngure, R. Chepkorir. Food Chemistry 113, 526–529 (2009).
  81. Bioactivity of Ocimum gratissimum L. oil and two constituents against five insect pests attacking stored food products. J. O. Ogendo, M. Kostyukovski, U. Ravid, J. C. Matasyoh, A. L. Deng, E. O. Omolo, S. T. Kariuki, E. Shaaya. Journal of Stored Product Research. 44, 328-334 (2008).
  82. Aloe Plant Extracts: An alternative Larvicide for Mosquito Control. J. C. Matasyoh, E. Wathuta, S. T. Kariuki,R. Chepkorir, J. Kavulani. African Journal of Biotechnology 7(7) 912-915 (2008). https://doi.org/10.5897/AJB08.018
  83. Chemical composition and antimicrobial activity of the essential oil of Ocimum gratissimum L. from different populations from Kenya. Lexa G. Matasyoh, Josphat C. Matasyoh, Francis N. Wachira, Miriam G. Kinyua, Anne W. Thairu Muigai and Titus K. Mukiama. Afr. J. Trad. CAM 5(2): 187-193 (2008).
  84. Distribution of piperitone oxide stereoisomers in Mentha and Micromeria species and their chemical syntheses. O. Narkov, J. C. Matasyoh, N. Dudai, E. Lewinsohn, A. A. Mayer, U. Ravid. Flavour Fragr. J. 22, 328-333 (2007). https://doi.org/10.1002/ffj.1801
  85. Chemical composition and antimicrobial activity of essential oil of Tarchonanthus camphoratus. Josphat C.  Matasyoh, Joyce J. Kiplimo, Nicholas M. Karubiu, Tiffany P. Hailstorks. Food chemistry 101, 1183-1187 (2007). https://doi.org/10.1016/j.foodchem.2006.03.021
  86. Chemical composition and antimicrobial activity of the essential oil of Ocimum gratissimum L. growing in Eastern Kenya. Lexa G. Matasyoh, Josphat C. Matasyoh, Francis N. Wachira, Miriam G. Kinyua, Anne W. Thairu Muigai and Titus K. Mukiama. African Journal of Biotechnology 6 (6), 760-765 (2007). https://doi.org/10.5897/AJB2007.000-2085
  87. Volatile oil constituents of Ocimum americanum L. occurring in Western Kenya. J. C. Matasyoh, J. O. Ogendo, A. L. Deng, E. O. Omolo. Bull. Chem. Soc. Ethiop. 20(1) 177-180 (2006).
  88. Field grain losses and insect pest management practices in subsistence agriculture: Farmers perspectives in Western Kenya. J. O. Ogendo, A. L. Deng, E. O. Omolo, J. C. Matasyoh Journal of Agriculture Science and Technology 8(1) 24-42 (2006).
  89. Chemical composition and antimicrobial activity of essential oil of Satureja biflora (Lamiaceae). Josphat C.  Matasyoh, Joyce J. Kiplimo, Nicholas M. Karubiu, Tiffany P. Hailstorks. Bull. Chem. Soc. Ethiop. 21(2), 1-6 (2006). http://DOI:10.4314/bcse.v21i2.21204  
  90. Chemical composition and antimicrobial activity of the essential oil of Leonotis nepetifolia. Josphat C.  Matasyoh, Joyce J. Kiplimo, Nicholas M. Karubiu. Int. J. BiochemiPhysics. 14(2) (2005).
  91. Chemical Constituents of Gomphocarpus physocarpus A. Josphat C. Matasyoh, Ronald Kimutai, and Graeme Nicholson. Int. J. BiochemiPhysics 13(1) 44-50 (2004).
  92. Synthesis and Structural Elucidation of the Nitrone 3,5-Diphenyl-5-methyl-pyrroline-1-oxide. J. C. Matasyoh and H. B. Stegmann. Int. J. BioChemiPhysics Vol. 8 and 9, No. 1&2 3-6 (1999).
  93. Synthesis and the Stereochemistry of the Spin Adducts of a New Chiral Spin Trap, 3,5-Diphenyl-5-methyl-pyrroline-1-oxide. J. C. Matasyoh, Ulrich Abram, P. Schuler, and H. B. Stegmann. Magn. Res. Chem. 36, 422-428 (1998).
  94. Synthesis and Spin Trapping Stereochemistry of the Chiral Spin Trap, 5,5-Dimethyl-3-phenylpyrroline-1-oxide. Josphat C. Matasyoh, Paul Schuler, Hartmut Stegmann, J. Lee Poyer, Melinda West, Edward G. Janzen. Magn. Res. Chem. 34, 351-359 (1996).
  95. Permutation Isomerization versus Metallotropy. EPR Investigation of Pentacoordinated Tin and Lead Compounds. Stegmann, H. B. and Matasyoh, J. C. Trends in Organometallic Chemistry. 1, 415-432 (1994).
  96. Levels of Mercury in Water, Fish, Sediments and Blood Samples from different Regions of Kenya. Kamau, G. N; Kinyanjui, L. W; Thairu, P. A; Matasyoh, J. C. Journal of BioChemPhysics, 1(1), 9-13 (1991).
CONFERENCES & INVITED PRESENTATIONS
  • 16th –  21st  June 1996: VII International Symposium on Free Radicals-Bardolino, Italy
  • 16th – 21st August 1999:Kenya Chemical Society Conference at JKUAT
  • 25th – 31st August 2001: NAPRECA Conference at K.I.C.C. Nairobi
  • 13th September 2003: K.C.S. AGM at Egerton University
  • 4th April 2005: NAPRECA workshop at the University of Nairobi, Kenya.
  • 1st – 12th August 2005: NAPRECA workshop/symposium in Antananarivo-Madagascar.
  • 22nd – 26th August 2005: KCS conference at Kenyatta University
  • 7th July 2006: Attended a NAPRECA seminar day at JKUAT
  • 17th – 21st July 2006: Egerton Unversity Research week.
  • 25th – 29th Sept. 2006: NAPRECA summer school in Gaborone, Botswana
  • 6th – 10th Nov. 2006: UNISTAFF REAL Conference at Kenyatta University, Kenya.
  • 29th Nov. – 1st Dec. 2006: DAAD conference at the University of Nairobi
  • 24th – 26th Jan. 2007: Green Chemistry Conference in Stellenbosch, Cape Town. South Africa
  • 2nd – 7th April 2007: VICRES Proposal writing workshop in Jinja, Uganda.
  • 16th – 26th July 2007: NAPRECA workshop and symposium in Kampala, Uganda
  • 18th – 19th Oct. 2007: Organised KDSA conference at Egerton University
  • 25th – 26th Oct. 2007: JKUAT International conference in Nairobi
  • 25th – 28th Feb. 2008: IOCD-ISDNP Joint symposium on natural products in Kasane, Botswana
  • 31st March –  2nd April 2009: World Conference on Education for Sustainable Development – Moving into the Second Half of the UN Decade. Bonn, Germany.
  • 7th –  9th October 2009: Humboldt Network workshop at the University of Oldenburg, Germany
  • 24th – 26th August 2010: Humboldt Kolleg workshop in Nairobi, Kenya with the theme: Synergy and Networking to Enhance Research and Development
  • 20th – 22nd July 2011: Workshop on Natural Products Chemistry in Tuebingen, Germany.
  • 9th – 10th Nov. 2011: International Deans Course Regional Workshop at Kenyatta University with the theme: Quality and Strategic Management in Higher Education Institutions in Eastern Africa.
  • 15th – 17th Nov. 2011: DAAD Conference in Nairobi with the theme: Capacity Development for the County Governments in the New Constitutional Dispensation in Kenya.
  • 21st – 26th Nov. 2011: International Health Workshop in Dar es Salaam, Tanzania with theme: Cross-cutting Agriculture and Health.
  • 15th – 17th February 2012: Second Conference of International Year of Chemistry held at the University of Nairobi.
  • 17th – 20th July 2012: International workshop at Sarova Taita Hills Hotel with the theme: The Future of Biodiversity Research in Africa: Scope, opportunities, collaboration, access and sharing benefits.
  • 15th – 16th November 2012: KDSA sponsored workshop held at Egerton with the theme: From Research to Action Towards the Attainment of Kenya Vision 2030.
  • 20th – 24th January 2013: The First International Conference on Pesticidal Plants held at ICIPE Nairobi
  • 23rd – 25th October 2013: Academia – Private Sector Forum and Exhibitions 2013 at Kenyatta International Conference Centre, Nairobi.
  • 4th – 7th December 2013: Kenya’s Soda Lakes Workshop held at KWS Training Institute in Naivasha
  • 3rd – 10th December 2013: The 15th Symposium of the Natural Products Research Network for Eastern and Central Africa (NAPRECA) held in Khartoum, Sudan.
  • 3rd – 4th February 2014: The 3rd Pest Management Conference of the Sudan, ARC, Wad Medan, Sudan
  • 6th – 8th March 2014: Humboldt Colloquium "The Power of Excellence in Science – Enhancing Academic Capacities in Africa" held at Safari Park Hotel in Nairobi.
  • 3rd September 2014: A presentation of my ERAfrica project to the Ministry of higher education officials at Jogoo House.
  • 16th – 18th September 2014: A presentation of my ERAfrica project at the ERAfrica kick-off conference held in Pretoria, South Africa.
  • 4th – 5th November 2014: Pan African Chemistry Network Symposium held at the University of Nairobi
  • 5th – 8th May 2015: Kenya Chemical Society held at the University of Nairobi
  • 15th – 16th January 2016: Humboldt Kolleg in Addis Ababa Ethiopia.
  • 6th – 8th April 2016: Humboldt Kolleg in Naivasha, Kenya entitled: Research and Networking: Laying the Foundation for the Sustainable Development Goals (SDG’s).
  • 18th November 2016: Presented a talk at the University of Sao Paulo in Brazil entitled: “Natural Products Research as a Tool for the Control of Crop, Animal and Human Disease Vectors”
  • 22nd – 24th November 2016: 3rd ResNet NPND Natural Products Research in Neglected Tropical Diseases Scientific meeting in Bogota, Columbia.
  • 6th – 10th February 2017: International Conference on Pesticidal Plants in Victoria Falls, Zimbabwe.
  • 4th – 7th April 2017: Proposal Development workshop in Entebbe Uganda
  • 4th- 5th May 2017: IV Symposium of Tropical Health/Cost Action CM 1307. (WG3 and WG4) Joint Meeting held in Pamplona‐Spain.
  • 20th – 21st June 2017: ERAFRICA workshop in Naivasha Kenya organized by NRF
  • 23rd – 26th October 2017: The 22nd conference of the African Association of Insect Scientists. (AAIS) held in Wad Medan, Sudan
  • 8th – 11th February 2018: NAPRECA Workshop held at Jomo Kenyatta University of Agriculture and Technology
  • 19th – 21st June 2018: “Humboldt Kolleg in Nanyuki” The Role of Alumni Networks in Mentorship and Collaboration in Multidisciplinary Research: Foundation for Kenya’s Vision 2030
  • 3rd – 7th December 2018: 4th  ResNet NPND Natural Products Research in Neglected Tropical Diseases Scientific meeting in Buenos Aires, Argentina.
  • 12th – 15th May 2019: Technical University of Berlin Alumni Meeting
  • 24th – 26th July 2019: Humboldt Annual Meeting in Berlin – World Café (Rapporteur) 
  • 12th – 15th September 2019: Humboldt Kolleg, Szczecin, Poland

SELECTED PANNEL DISCUSSIONS

  • 2nd April 2009: Sustainability within the organic chemistry lab course. Bonn, Germany
  • 28th Sept. 2011: Internationalisation Strategy for Research in Germany – German Parliament. Berlin, Germany.
  • 2nd Nov. 2011: Tele-conference on Innovations at Egerton University with Ministry of Higher Education officials and experts.
TEACHING AREAS
  1. Organic chemistry
  2. NMR Spectroscopy and mass spectrometry
POSTGRADUATE SUPERVISION
MASTERS LEVEL :

Successfully supervised over 25 postgraduate students and several still under supervision.

OTHER SOCIETIES
  1. Kenya Chemical Society
  2. NAPRECA – Natural Products Research Network for Eastern and Central Africa
  3. Green Chemistry – Africa Chapter
  4. Global Malaria Alliance
  5. Pan African Chemistry Network
  6. ResNet NPND– Research Network Natural Products against Neglected Diseases
  7. International Society of Pesticidal Plants
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